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Molecular Genetics and Microbiology

DEPARTMENT CHAIR:                   JORGE BENACH
GRADUATE PROGRAM DIRECTOR: JANET HEARING

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Jointly Authored Publications

Bublitz, D.C., Noah, C.E., Benach, J.L., and Furie, M.B. (2010).  Francisella tularensis suppresses the proinflammatory response of endothelial cells via the endothelial protein C receptor.  Journal of Immunology, 185(2): 1124-1131.

LaRocca, T.J., Crowley, J.T., Cusack, B.J., Pathak, P., Benach, J., London, E., Garcia-Monco, J.C., and Benach, J.L. (2010).  Cholesterol lipids of Borrelia burgdoferi form lipid rafts and are required for the bactericidal activity of a complement-independent antibody.  Cell Host and Microbe, 8(4): 331-342.

Karen, K.A.,and Hearing, P. (2011).  Adenovirus core protein VII protects the viral genome from a DNA damage response at early times after infectionJournal of Virology, 85(9): 4135-4142.

Yount, J.S., Tsou, L.K., Dossa, P.D., Kullas, A.L., van der Velden, A.W., and Hang, H.C. (2010).  Visible fluorescence detection of type III protein secretion from bacterial pathogensJournal of the American Chemical Society, 132(24): 8244-8245.

Zheng, Y., Lilo, S., Brodsky, I.E., Zhang, Y Medzhitov, R., Marcu, K.B., and Bliska, J.B.  (2011).  A Yersinia effector with enhanced inhibitory activity on the NKkB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophagesPLoS Pathogens, 7(4):e1002026.

Mulligan, E.A., Hatchwell, E., McCorkle, S.R., and Dunn, J.J. (2010).  Differential binding of Escherichia coli McrA protein to DNA sequences that contain the dinucleotide m5CpGNucleic Acids Research, 38(6):1997-2005.

Navin, N.,Kendall, J., Troge, J., Andrews, P, Rodgers, L., McIndoo, J., Stepansky, A., Levy, D., Esposito, D., Muthuswamy, L., Krasnitz, A., McCombie, W.R., Hicks, J., and Wigler, M.  (2011).  Tumor evolution inferred by single-cell sequencingNature, 472(7341): 90-94.

Gunasekera, A., Alvarez, F.J., Douglas, L.M., Wang, H.X., Rosebrock, A.P., and Konopka, J.B. (2010).  Identification of GIG1, a GlcNAc-induced gene in C. albicans needed for normal sensitivity to the chitin synthase inhibitor nikkomycin z. Eucaryotic Cell, 9(10): 1476-1483.

Felek, S., Jeong, J.J., Runco, L.M., Murray, S., Thanassi, D.G., and Krukonis, E.S.  (2011).  Contributions of chaperone/usher systems to cell binding, biofilm formation and Yersinia pestis virulenceMicrobiology, 157(3): 805-818.

Liu, Y., Wang, C Mueller, S., Paul, A.V., Wimmer, E., and Jiang, P. (2010).  Direct interaction between two viral proteins, the nonstructural protein 2CATPase and the capsid protein VP3, is required for enterovirus morphogenesis.  PLoS Pathogens, 6(8): e1001066.

Zeituni, A.E., Carrion, J., and Cutler, C.W. (2010).  Porphyromonas gingivalis-dendritic cell interactions:  consequences for coronary heart disease.  Journal of Oral Microbiology, (2): 5782-5789.

Zeituni, A.E., McCaig, W., Scisci, E., Thanassi, D.G., and Cutler, C.W. (2010).  The native 67 kDa minor fimbriae of Porphyromonas gingivalis:  a novel glycoprotein with DC-SIGN-targeting motifs.  Journal of Bacteriology, 192(16): 4103-4110.

Zheng, Y., Lilo, S., Brodsky, I.E., Zhang, Y Medzhitov, R., Marcu, K.B., and Bliska, J.B.  (2011).   A Yersinia effector with enhanced inhibitory activity on the NKkB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophagesPLoS Pathogens, 7(4):e1002026.


Abstracts, Conferences/Colloquia, Invited Talks, Presentations

Bublitz, D.C. (2011).  Characterizing How Francisella tularensis Suppresses the Proinflammatory Response of Endothelial Cells.  Gordon Research Conference on Microbial Adhesion and Signal Transduction.  Newport, RI.

Navin, N. (2010).  Tumor Progression Revealed by Sequencing 100 Single Cells in a Heterogeneous Breast Carcinoma.  James Watson Cancer Symposium. Suzhuo, China.

Zheng, Y. (2010).  The Effector YopJKIM Activates Caspace-1 and Induces Caspace-1 Independent Necrotic Death in Yersinia-infected Macrophages.  Gordon Research Conference on Cell Death. Newport, RI.