DEPARTMENT CHAIR:                   ROBERT HALTIWANGER
GRADUATE PROGRAM DIRECTOR: ROLF STERNGLANZ

Akgul G, Wollmuth, L. (2010).  Expression pattern of membrane-associated guanylate kinases in interneurons of the visual cortex.  The Journal of Comparative Neurology, 518(24): 4842-54.

Pavlaki, M., Zucker, S., Dufour, A., Calabrese, N., Bahou, W., and Cao, J. (2010).  Furin functions as a nonproteolytic chaperone for matrix metalloproteinase-28: MMP-28 propeptide sequence requirement.  Biochemistry Research International,  DOI:10.1155/2011/630319.

Noah CE, Malik M, Bublitz DC, Camenares D, Sellati TJ, Benach JL, Furie MB. (2010).  GroEL and lipopolysaccharide from Francisella tularensis live vaccine strain synergistically activate human macrophages. Infect Immun, 78(4):1797-806. Epub 2010 Feb 1. PubMed PMID: 20123721; PubMed Central PMCID: PMC2849404.

Callender, T. and N. M. Hollingsworth. (2010).  Mek1 suppression of meiotic double strand break repair is specific to sister chromatids, chromosome autonomous and independent of REC8 cohesin complexes., Genetics, (2): 185:1-12.

Clower CV*, Chatterjee D*. Wang Z, Cantley LC, Vander Heiden MG, Krainer AR. (2010).  The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism.   PNAS; 107:1894-1899.

Pan Ji-An, Ullman Erica, Dou Z,  Zong Wei-Xing. (2011).  Inhibition of protein degradation induces apoptosis through an LC3-mediated activation of caspase-8 at intracellular membranes. Molecular and Cellular Biology,  (15):3158-70.

 Dou Z, Pan Ji-An, Lin Richard, Zong Wei-Xing. (2011).  The beta identity of class I PtdIns3K: A positive role of p110β in autophagy revealed,  Autophagy,  7(2):246-7.

 Dou Z, Chattopadhyay Mohar, Pan Ji-An, Guerriero Jennifer, Jiang Ya-Ping, Ballou Lisa, Yue Zhenyu, Lin Richard, Zong Wei-Xing. (2010).  The Class IA phosphatidylinositol 3-kinase p110β subunit is a positive regulator of autophagy,  Journal of Cell Biology 15;191(4):827-43.

Hornak V, Ahuja S, Eilers M, Goncalves, J. A Sheves M, Reeves PJ, Smith SO. (2010).  Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints,  Journal of  Molecular Biology. 396(3):510-27.

Dou Z, Chattopadhyay M, Pan JA, Guerriero JL, Jiang YP, Ballou LM, Yue Z, Lin RZ, Zong WX. (2010).  The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy, Journal of Cell Biology. 15;191(4):827-43.  PubMed PMID: 21059846.

Penzo, M., Molteni, R., Suda, T., Samaniego, S., Raucci, A., Habiel, D.M., Miller, F., Jiang, H., Li J., Pardi, R., Palumbo,R., Olivotto, E., Kew, R.R., Bianchi, M.E., and Marcu, K.B. (2010).  HMGB1 chemotactic responses differentially depend on IKKa and IKKb to drive two NF-kB pathways.  Journal of Immunology,  (184): 4497-509.

Zhang, J., D.M. Habiel, M. Ramadass and R.R. Kew. (2010).  Identification of two distinct cell binding sequences in the vitamin D binding protein.  Biochimica et Biophysica Acta, (1803):623-629.  PMID:20211661.

Hui-Ju, Y., and Neiman, A.M. (2010).  A guanine nucleotide exchange factor is a component of the meiotic spindle pole body.  Schizosaccharomyces pombe. Molecular Biology of the Cell,  (21): 1272-1281.

Jadali A Ghazizadeh S. (2010).   Protein kinase D is implicated in the reversible.commitment to differentiation in primary cultures of mouse keratinocytes. Journal of  Biolological Chemistry 23;285(30):23387-97. Epub 2010 May 12. PubMed PMID: 20463010;PubMed Central PMCID: PMC2906330.

Jadali, A and  Ghazizadeh, S. (2010).  Calcium-induced epidermal differentiation is a reversible process regulated by PKD. Annual meeting of the Society of Investigative Dermatology. Atlanta, Georgia. Abstract published in The Journal of Investigative Dermatology, (130): S95.

Jiang, P., Jahan, N., Wimmer, E. (2010).  Mechanisms of Pathogenesis of Enteroviruses and Strategies to Mitigate Enteroviral Virulence. In D. Raghunath (Ed.), Mechanisms of Microbial Pathogenesis,  (41-76).   India: Macmillan Publishers India Ltd.

Kok F. O., Shepherd I. T. and Sirotkin H. I. (2010).Churchill and Sip1a repress fibroblast growth factor signaling during zebrafish somitogenesis, Developmental Dynamics, (239): 548-58.

Liao, MC., Van Nostrand WE. (2010).  Degradation of Soluble and Fibrillar Amyloid ß-Protein by matrix metalloproteinase (MT1-MMP), Biochemistry, (49): 1127-113.

Lighthouse, J.K., Zhang, L., Hsieh, J.C., Rosenquist, T., and Holdener, B.C. (2010).  MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm, Dev Dyn. Epub ahead of print, (3): 566-88.

Lin, G., Aranda, V., Muthuswamy, S.K., Tonks, N.K. (2011).  Identification of PTPN23 as
a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function
                                screen of the “PTP-ome.” Genes & Development,  (25):1412-1425.

Lo, H.C. and N. M. Hollingsworth. (2011).  Using the semi-synthetic epitope system to identify direct substrates of the meiosis-specific budding yeast kinase, Mek1.  Methods of  Molecular Biology, (745):  135-149.

Gorbunova EE, Gavrilovskaya IN, Pepini T, Mackow ER. (2011).  VEGFR2 and Src kinase inhibitors suppress ANDV induced endothelial cell permeability. Journal of Virology,  (85): 2296-303.

Matthys, V. Gorbunova, EE. Gavrilovskaya, IN, Pepini T. and Mackow. ER (2011).  The C-terminal 42 residues of the TULV Gn protein regulate interferon induction. Journal of Virology, (85): 4752-60.

Pepini, T., Gorbunova, EE., Gavrilovskaya, IN., Mackow, JE, Mackow, ER (2010).  Andes virus regulation of cellular MicroRNAs contributes to hantavirus induced endothelial cell permeability. Journal of Virology,( 84): 11929-11936.

Prieto-Echagüe, V., Gucwa, A., Craddock, B. P., Brown D. A. and Miller, W. T. (2010).  Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1. Journal of Biological Chemistry, 2;285(14):10605-15.

Zhang, J., D.M. Habiel, M. Ramadass and R.R. Kew. (2010).  Identification of two distinct cell binding sequences in the vitamin D binding protein.  Biochim Biophys Acta,  1803:623-629.  PMID:20211661.

Fernandez-Valdivia, R., Takeuchi, H., Samarghandi, A., Lopez, M., Leonardi, J., Rana, N.A., Haltiwanger, R.S., and Jafar-Nejad, H. (2010) .  Regulation of the mammalian Notch signaling by the protein O-glucosyltransferase rumi.  Glycobiology,  (20): 1456a.

Takeuchi, H., Taylor, P., Kakuda, S., Rana, N.A., Handford, P.A., and Haltiwanger, R.S. (2010).  Examining how O-Fucose and O-Glucose affect notch-ligand binding.  Glycobiology,  (20): 1484a.

Leonardi, J., Fernandez-Valdivia, R., Rana, N.A., Li, Yi-Dong, Simcox, A., Haltiwanger, R.S., Jafar-Nejad, H. (2010).  O-Glucosylation of Multiple EGF Repeats of Notch by Rumi is Required for Optimal Notch Signaling. Glycobiology,  (20): 1483a.

Rana, N.A., Nita-Lazar, A., Kakuda, S., and Haltiwanger, R.S. (2010).  Analysis of O-Glucosylation on Mouse Notch1. Glycobiology.   (20): 1467a.

Rana, N.A., Xu, M.L., Moss, H., Rab, A., Leonardi, J., Jafar-Nejad, H., and Haltiwanger, R.S. (2010).  Fringe benefits:  Analysis of O-glycosylation and fringe elongation on the extracellular domain of Drosophila Notch. Glycobiology.  (20): 1486a.

San Luis, B, Sondgeroth B, Nassar N, Carpino N. (2011).  Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways. Journal of Biological Chemistry.  286(18):15943-54.

Shang, Y; Nguyen, H. Wickstrom, L. Okur, A. Simmerling, C. (2011).  Improving the description of salt bridge strength and geometry in a Generalized Born model. J Mol Graph Model. 29 (5): 676-84.

Stawowczyk, M. Sarah Van Scoy, Prasanna K. Kumar, and Nancy C. Reich. (2011).  The interferon stimulated gene 54 promotes apoptosis. Journal of Biological Chemistry.  (286):7257-66.

Hagn F, Klein C, Demmer O, Marchenko N, Vaseva, A., Moll UM., Kessler H. (2010).  BclxL changes conformation upon binding to wild-type but not mutant p53 DNA binding domain. J Biol Chem. 285(5):3439-50.

Vasudevan, D., Majerus, E., and Haltiwanger, R.S. (2010).  Impact of O-Fucosylation on the Folding and Secretion of Thrombospondin Type-1 Repeat Containing Proteins.  Glycobiology.  (20): 1502a.

Dou Zhixun, Chattopadhyay Mohar, Lin Richard, and Zong Wei-Xing. (2011).  The class IA PI3K p110β subunit is a positive regulator of autophagy. PI 3-Kinase Signaling Pathways, Keystone Symposia, CO.

Evensen, Nikki., Kuscu, C., Zarrabi, K., Zucker, S., Cao, J. (2011).  Characterization of cancer endoplasmic reticulum invasion gene (CERIG): A novel endoplasmic reticulum protein. Vermont Academy, Saxtons River, VT. 

Evensen, Nikki, Li, J., Zucker, S., Cao, J. (2011).  Development of a three dimensional invasion assay for high-throughput anti-cancer drug screening. Albany, NY.

Fagbemi, Adebanke. (2010).  Multiple Domains for PCNA Interaction in XPG and their Effects on NER. Structural Cell Biology of DNA Repair Machines. Berkeley, CA.

Habiel, David M Glenda Trujillo, Jianhua Zhang, Richard R. Kew. (2010).  Cofactor amplification of C5a/C5a des Arg chemotactic activity in physiological fluids. 
Presented at the XXIII International Complement Workshop, New York, NY.  Abstract published in Molecular Immunology 47,2290.

Karaayvaz, Mihriban. (2011).  Expression of miR-205 is significantly associated with prognosis of endometrial cancer. Orange County Convention Center, Orlando, FL.

Karaayvaz, Mihriban. (2011).  Prognostic significance of miR-215 in colon cancer. Orange County Convention Center, Orlando, FL.

Lin, Guang, Aranda, V., Muthuswamy, S.K., Tonks, N.K. (2011).  Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function
screen of the “PTP-ome.”  The Biology of Cancer: Microenvironment, Metastasis &
Therapeutics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. (talk).

Ramadass, Mahalakshmi , Richard R. Kew. (2010).  Complement activation induced modification of the vitamin D binding protein.  Presented at the XXIII International Complement Workshop, New York, N.Y. August 02, 2010.  Abstract published in Molecular Immunology.   47:2286 (2010).

Shang, Yi (2011).  ACS CCG Research Excellence award,  $1,150 and 1 year license of MOE software. Chemical Computing Group, Montreal, Canada.