Graduate Course Offerings
(Current course information is available via the Graduate Bulletin.)

MOLECULAR GENETICS MCB 503, FALL
Covers gene structure and regulation in prokaryotic and eukaryotic organisms, mutational analysis and mapping, transposable elements, and biological DNA transfer mechanisms. Bacteriophage as well as lower and higher eukaryotic systems are used to illustrate aspects of molecular genetic structure and function.

EXPERIMENTAL MOLECULAR & CELLULAR BIOLOGY MCB 509/510 ,FALL & SPRING
An introduction to modern biochemical research techniques. The student spends a half term in the laboratory of each of four different members of the staff selected in consultation with the course director. In each laboratory the student participates in some aspect of the ongoing research pursued by the faculty member. Prerequisite: matriculation in graduate program or permission of instructor.

PHYSICAL BIOCHEMISTRY MCB 512 , SRPING
Theoretical principles and experimental methods used in the study of proteins and nucleic acids, e.g., spectroscopy, magnetic resonance and diffraction.

MEMBRANE BIOCHEMISTRY MCB 517 , FALL
Examines the molecular architecture of membranes; the structure, organization, functions, and assembly of lipids and proteins in biological membranes. This course is also offered as BSB 517.

GRADUATE BIOCHEMISTRY I MCB 520, FALL
Several topics in modern biochemistry are treated at an advanced level. Topics covered include protein structure, methods of peptide and protein analysis, purification, enzyme kinetics and mechanisms, and enzyme regulation.

ORGANELLE DEVELOPMENT MCB 529
This course is concerned primarily with the development of the mitochondrion and the chloroplast. Subjects will include the biogenesis of these organelles and their relation to the interaction with the nucleus. Emphasis will be on genetic and biochemical analysis. Prerequisite: matriculation in graduate program or permission of instructor.

GRADAUTE JOURNAL CLUB MCB 531/532 ,FALL & SPRING
Seminars are given by graduate students on current literature in the fields of biochemistry, molecular biology, cell biology or developmental biology. Prerequisite: matriculation in graduate program or permission of instructor.

DISSERTATION RESEARCH MCB 599
Original investigation under the supervision of a member of the staff. Prerequisite: matriculation in graduate program or permission of instructor.

COLLOQUIUM IN MOLLECULAR & CELLULAR BIOLOGY MCB 601/602 FALL & SPRING
A weekly series of talks and discussions by visiting scientists covering current research and thinking in various aspects of molecular and cellular biology. Required for all MCB graduate students. Attendance is mandatory. Visitors welcome. Prerequisite: matriculation in graduate program or permission of instructor.

STUDENT SEMINAR IN MOLLECULAR & CELLULAR BIOLOGY M CB 603/604 FALL & SPRING
Seminars given by graduate students on the progress of their own thesis research. Required of all students every term in which they are registered in Graduate Studies in Molecular Biology and Biochemistry. Attendance is mandatory. Visitors welcome. Prerequisite: matriculation in graduate program or permission of instructor.

CELL BIOLOGY MCB 656, SPRING
Introduction to the structural and functional organization of cells and tissues and to the way structure relates to function. Particular emphasis is placed on nuclear and chromosomal structure, signal transduction, protein translocation, the cytoskeleton and the extracellular matrix. The interaction of cellular structures and components and their regulation is stressed as is the organization and interaction of cells in tissues. The course is comparative and includes examples of cells and tissues from vertebrates, invertebrates, plants, and prokaryotic systems.

PRINCIPLES OF DEVELOPMENT MCB 657, FALL
This course deals with developing systems at all levels from the morphological to the molecular. Illustrative material from both animal and plant kingdoms is used. Special attention is given to gametogenesis, genetic control of early development, transcriptional and translational control of protein synthesis, the role of cell division and cell movements, and cell-to-cell interactions in defining developing systems.

DISSERTATION RESEARCH ON CAMPUS MCB 699 , FALL & SPRING
Prerequisite: Must be advanced to candidacy (G5). Major portion of research must take place on SBU campus, at Cold Spring Harbor , or at the Brookhaven National Lab. Prerequisite: matriculation in graduate program or permission of instructor is deemed comparable.

SUMMER RESEARCH MCB 800
Prerequisite: matriculation in graduate program or permission of instructor.

COMPUTATIONAL METHODS IN BIOCHEMISTRY & STRUCTURAL BIOLOGYV BSB 515, FALL
Computational methods used in sequence searching and analysis, bioinformatics, graphical analysis of proteins, and nucleic acids. Prerequisite: This class is restricted to first year BSB, HBM & HBH PhD students and 2nd year MCB PhD students. Exception requires approval from the course instructor.

GENERAL PATHOLOGY HBP 531, SPRING
Introduction to the nature and causes of disease, death, reaction to injury, and repair. Analysis of associated structural changes in cells and tissues, with reference to their functional correlates.

IMMUNOLOGY HBP 533, FALL
Principles of immunology for graduate students in the biological sciences, including definition of antigens and antibodies, specificity of the immune response, serological quantitation of proteins and hormones, immunoglobulin structure, the genetics of immunoglobulin synthesis, cellular cooperation in the immune response, hypersensitivity, tolerance, and transplantation.

 

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