Graduate Course Offerings
Current course information is available via the Graduate Bulletin .)

Core Lecture Courses

INTRODUCTION TO STRUCTURAL BIOLOGY BSB 512, SPRING
A broad overview of the theoretical principles and experimental methods used in structural studies of proteins and nucleic acids. The course covers the fundamentals and applications of absorption spectroscopy, including both circular and linear dichroism, vibrational spectroscopy, including infrared and Raman, fluorescence spectroscopy, nuclear magnetic resonance spectroscopy, and X-ray diffraction.

COMPUTATIONAL METHODS IN BIOCHEMISTRY AND STRUCTURAL BIOLOGY BSB 515, FALL
An introductory course in the computational methods used in biochemistry and structural biology. The course emphasizes the resources available on the World Wide Web for sequence searching and analysis, bioinformatics, the prediction of protein secondary and tertiary structure, and the graphical analysis of proteins and nucleic acids.

MEMBRANE BIOCHEMISTRY BSB 517, FALL
This course extends the graduate course in biochemistry to encompass the molecular architecture of membranes and the organization, functions, and assembly of lipids and proteins in biological membranes.

GRADUATE BIOCHEMISTRY BSB 520, FALL
Several topics in modern biochemistry are treated at an advanced level. Topics covered include protein structure, methods of peptide and protein analysis and purification, enzyme kinetics and mechanisms, and enzyme regulation.

Examples of Elective Courses

ADVANCED STRUCTURAL BIOLOGY BSB 580, SPRING
Advanced topics in X-ray crystallography and NMR spectroscopy. Current theory, experimental methods, and applications are covered in detail for advanced students.

CELL BIOLOGY MCB 656, SPRING
An introduction to the structural and functional organization of cells and tissues and the way structure relates to function. Particular emphasis is placed on nuclear and chromosomal structure, signal transduction, protein translocation, the cytoskeleton, and the extracellular matrix. The course focuses on the interaction of the cellular structures and components and their regulation as well as the organization and interaction of cells in tissues. The course is comparative and includes examples of cells and tissues from vertebrates, invertebrates, plants, and prokaryotic systems.


MOLECULAR GENETICS MCB 503
Introduces the classical work and current developments in lower and higher genetic systems. Covers gene structure and regulation in prokaryotic and eukaryotic organisms, mutational analysis and mapping, transposable elements, and biological DNA transfer mechanisms. Bacteriophage as well as lower and higher eukaryotic systems are used to illustrate aspects of molecular genetic structure and function. This course is offered as both MCB 503 and HBM 503.

Non-Lecture Courses

EXPERIMENTAL BIOCHEMISTRY AND STRUCTURAL BIOLOGY BSB 509, 510, FALL AND SPRING
An introduction to current research methods used in biochemistry and structural biology. The student spends a half-semester in the laboratory of each of three different members of the faculty. In each laboratory the student participates in some aspect of the research being pursued by the faculty member.

GRADUATE RESEARCH BSB 599, FALL AND SPRING
Original investigation undertaken with the supervision of a faculty member.

COLLOQUIUM IN BIOCHEMISTRY AND STRUCTURAL BIOLOGY BSB 601, 602, FALL AND SPRING
A weekly series of talks and discussions by visiting scientists in which current research and thinking in various aspects of biochemistry and structural biology will be presented. This course is required every semester of all students registered in the Graduate Program in Biochemistry and Structural Biology. Attendance is mandatory. Visitors are welcome.

JOURNAL CLUBS IN BIOCHEMISTRY AND STRUCTURAL BIOLOGY
BSB 531,532, FALL AND SPRING
Seminars given by graduate students on the progress of their own thesis research. Required every semester of all students registered in the Graduate Program in Biochemistry and Structural Biology. Attendance is mandatory.
Visitors are welcome.

DISSERTATION RESEARCH BSB 699, FALL AND SPRING
Original investigations undertaken as part of the Ph.D. program under supervision of a research committee.

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